Chenlin Hu
Research Scientist
Department of Pharmacy Practice and Translational Research
Office
University of Houston College of Pharmacy
Health 2, Room 4040
4349 Martin Luther King Boulevard
Houston, TX 77204-5039
Contact
chu10@central.uh.edu | 832-842-4004
Research/Academic Interests
My research develops cutting-edge knowledge and technologies to address these urgent problems in public health microbiology with focus on freshwater harmful algal blooms and clinical multidrug resistance. My research on freshwater harmful algal blooms focuses on the cause and control of harmful algal blooms, evaluation and management of algal toxin risks, analysis of algal toxin and algal bioactive, UV-absorbing compound mycosporine-like amino acids. My present research on clinical multidrug resistance focuses on developing cutting-edge technologies for pharmaceutical and metabolite detection, advanced cell imaging, and gene editing to advance the development of new drugs.
- Ph.D. in Environmental Science, Chinese Academy of Sciences, China (2012)
- Joint Ph.D. training and education program by German Academic Exchange Service (DAAD) in Biology, Humboldt University of Berlin, Germany (2009-2011)
- Bsc., in Applied Chemistry, Wuhan University, China (2005)
- Hu C, R Huynh-Phan R, Rodriguez Robles KM, Eubank TA, Garey KW. Recovery and stability of omadacycline 150 mg crushed tablets dispersed in food, water, or administered via nasogastric tube. Open Forum Infect Dis. 2026, 13 (2), ofag011.
- Jo J, Carlson TJ, Hu C, Williamson JC, Belin YT, Horvath TD, Haidacher SJ, Bassères E, Begum K, Alam MJ, and Garey KW. Fecal pharmacokinetics, microbiome, and bile acid changes in healthy subjects given intravenous followed by oral omadacycline; a phase 1 clinical trial. J Antimicrob Chemother, 2025, dkaf278.
- Wei N, Hu C, Dittmann E, Song L, Gan N. The biological functions of microcystins. Water Research, 2024, 262: 122119.
- Hu C, W Wang, J Jo, Garey KW. Development and validation of LC-MS/MS for quantifying omadacycline from stool for gut microbiome studies. J Chromatogr B, 2024, 1236:124057.
- Jo J, Hu C, Begum K, Wang W, Le TM, Agyapong S, Hanson BM, Ayele H, Lancaster C, Alam MJ, Gonzales-Luna AJ, and Garey KW. Fecal Pharmacokinetics and Gut Microbiome Effects of Oral Omadacycline versus Vancomycin in Healthy Volunteers. J Infect Dis, 2024, 229(1):273-281.
- Eubank TA, Hu C, Gonzales-Luna AJ, and Garey KW. Detectable Vancomycin Stool Concentrations in Hospitalized Patients with Diarrhea Given Intravenous Vancomycin. Pharmacoepidemiology. 2023, 2, 283-288.
- Mason CS, Avis T, Hu C, Nagalingam N, Mudaliar M, Coward C, Begum K, Gajewski K, Alam MJ, Bassères E, Moss S, Reich S, Duperchy E, Fox KR, Garey KW, and Powell DJ. The novel DNA binding mechanism of ridinilazole, a precision Clostridiodes difficile antibiotic. Antimicrob Agents Chemother. 2023, e0156322.
- Hu C, Wang W, Garey KW. Heterogeneity and lyophilization comparison of stool processing for gastrointestinal bile acid measurement by LC-MS/MS. J Chromatogr B, 2023(1214), 123569.
- Hu C, Byeda N, and Garey K. A Vancomycin HPLC Assay for Use in Gut Microbiome Research, Microbiology Spectrum, 2022,10(3):e0168821
- Garey KW, McPherson J, Dinh AQ, Hu C, Jo J, et al. Efficacy, Safety, Pharmacokinetics, and Microbiome Changes of Ibezapolstat in Adults with Clostridioides difficile Infection: A Phase 2a Multicenter Clinical Trial. Clin Infect Dis, 2022, 75 (7), 1164–1170.
- Hu C, Fong G. Wurster ST, Kontoyiannis D, Beyda NBD. Clumping morphology influences virulence uncoupled from echinocandin resistance in Candida glabrata. Microbiology Spectrum 2022, 10 (1) e01837-21.
- Hu C, Zuo Y, Peng L, Gan N, Song L.. Widespread Distribution and Adaptive Degradation of Microcystin Degrader (mlr-Genotype) in Lake Taihu, China. Toxins, 2021, 13:864.
- Hu C and Rzymski P. Programmed Cell Death-Like and Accompanying Release of Microcystin in Freshwater Bloom-Forming Cyanobacterium Microcystis: From Identification to Ecological Relevance. Toxins, 2019, 11:706.
- Hu C, Voeller G, Suessmuth R, Dittmann E, Kehr J.C. Functional assessment of mycosporine-like amino acids in Microcystis aeruginosa strain PCC 7806. Environ Microbiol 2015, 17: 1548-1559.
- Best Postdoc Poster Presentation Award, Second Place, University of Houston (2018)
- DAAD (German Academic Exchange Service) scholarship for Joint Ph.D. training and education program (2009-2011)
- Outstanding Graduate, Institute of Hydrobiology, Chinese Academy of Sciences (2008)
- Outstanding Undergraduate, Wuhan University, China (2004)