Micah B. Castillo, Sakuni Rankothgedera, Shiyanth Thevasagayampillai, Aaranyah Kandasamy,
Jaila Lewis, Cole Woody, Martiela Vaz de Freitas, Dinler Amaral Antunes, Randa El-Zein,
Preethi H. Gunaratne. Identification of immunogenic KIF5B-RET fusion neopeptides driving
immune stimulation in tumor specific CD8+ T cells. Front Immunol., 29 October 2025, Sec. Vaccines and Molecular Therapeutics; Volume 16 - 2025 | doi.org/10.3389/fimmu.2025.1635810
Mistretta B, Rankothgedera S, Castillo M, Rao M, Holloway K, Bhardwaj A, El Noafal
M, Albarracin C, El-Zein R, Rezaei H, Su X, Akbani R, Shao XM, Czerniecki BJ, Karchin
R, Bedrosian I, Gunaratne PH*. Chimeric RNAs reveal putative neoantigen peptides for
developing tumor vaccines for breast cancer. Front Immunol. 2023;14:1188831. eCollection 2023. PubMed PMID: 37744342; PubMed Central PMCID:
PMC10512078.
Sandra L. Grimm, Emily F. Mendez, Laura Stertz, Thomas D. Meyer, Gabriel R. Fries,
Tanmay Gandhi, Rupa Kanchi, Sudhakar Selvaraj, Antonio L. Teixeira, Thomas R. Kosten,
Preethi Gunaratne, Cristian Coarfa and Consuelo Walss-Bass. MicroRNA-mRNA networks
are dysregulated in opioid use disorder postmortem brain: Further evidence for opioid-induced
neurovascular alterations. Front. Psychiatry, 12 January 2023. Sec. Molecular Psychiatry. Volume 13. doi.org/10.3389/fpsyt.2022.1025346
Nicole Prodan, Faheem Ershad, Arfaxad Reyes-Alcaraz, Luge Li, Brandon Mistretta, Lei
Gonzalez, Zhoulyu Rao, Cunjiang Yu, Preethi H. Gunaratne, Na Li, Robert J. Schwartz,
Bradley K. McConnell. Direct reprogramming of cardiomyocytes into cardiac Purkinje-like
cells iScience. 2022 Nov 18; 25(11): 105402. Published online 2022 Oct 20. doi: 10.1016/j.isci.2022.105402.
PMCID: PMC9646947
Jose Thaiparambil, Jianrong Dong, Sandra L Grimm, Dimuthu Perera, Chandra Shekar R
Ambati, Vasanta Putluri, Matthew J Robertson, Tajhal D Patel, Brandon Mistretta, Preethi
H Gunaratne, Min P Kim, Jason T Yustein, Nagireddy Putluri, Cristian Coarfa, Randa
El-Zein. Integrative metabolomics and transcriptomics analysis reveals novel therapeutic
vulnerabilities in lung cancer. Cancer Med. 2022 Jun 8. PMID: 35676822
Sarah E Woodfield, Brandon J Mistretta, Roma H Patel, Aryana M Ibarra, Kevin E Fisher,
Stephen F Sarabia, Ilavarasi Gandhi, Jacquelyn Reuther, Zbigniew Starosolski, Andrew
Badachhape, Jessica Epps, Barry Zorman, Aayushi P Shah, Samuel R Larson, Rohit K Srivastava,
Yan Shi, Andres F Espinoza, Saiabhiroop R Govindu, Richard S Whitlock, Kimberly Holloway,
Angshumoy Roy, Pavel Sumazin, Ketan B Ghaghada, Dolores Lopez-Terrada, Preethi H Gunaratne,
and Sanjeev A VasudevanHepT1-derived murine models of high-risk hepatoblastoma display
vascular invasion, metastasis, and circulating tumor cells. Open Biol. MS ID#: BIOLOPEN/2021/058973
(Accepted)
Divya Ravirala, Brandon Mistretta, Preethi H Gunaratne, Guangsheng Pei, Zhongming
Zhao, Xiaoliu Zhang. Co-delivery of novel bispecific and trispecific engagers by an
amplicon vector augments the therapeutic effect of an HSV-based oncolytic virotherapy.
J Immunother Cancer. 2021; 9(7): e002454. Published online 2021 Jul 6. doi: 10.1136/jitc-2021-002454.
PMCID: PMC8261877
Yajuan Li, Zhi Tan, Yaohua Zhang, Zhao Zhang, Qingsong Hu, Ke Liang, Jun Yao, Youqiong
Ye, Yi-Chuan Li, Chunlai Li, Lan Liao, Jianming Xu, Zhen Xing, Yinghong Pan, Sujash
S. Chatterjee, Tina K. Nguyen, Heidi Hsiao, Sergey D. Egranov, Nagireddy Putluri,
Cristian Coarfa, David H. Hawke, Preethi H. Gunaratne, Kuang-Lei Tsai, Leng Han, Mien-Chie
Hung, George A. Calin, Fares Namour, Jean-Louis Guéant, Ania C. Muntau, Nenad Blau,
V. Reid Sutton, Manuel Schiff, François Feillet, Shuxing Zhang, Chunru Lin, Liuqing
Yang. A noncoding RNA modulator potentiates phenylalanine metabolism in mice Science. 2021 Aug 6; 373(6555): 662-673. PMCID: PMC9714245
Yajuan Li, Yaohua Zhang, Qingsong Hu, Sergey D. Egranov, Zhen Xing, Zhao Zhang, Ke
Liang, Youqiong Ye, Yinghong Pan, Sujash S. Chatterjee, Brandon Mistretta, Tina K.
Nguyen, David H. Hawke, Preethi H. Gunaratne, Mien-Chie Hung, Leng Han, Liuqing Yang,
Chunru Lin. Genome Med. 2021; 13: 137. Published online 2021 Aug 28. doi: 10.1186/s13073-021-00937-4.
Functional significance of gain-of-function H19 lncRNA in skeletal muscle differentiation
and anti-obesity effects. PMCID:PMC8403366
Stewart Fannin, Jonathan Rangel, Abiodun P. Bodurin, Tannon Yu, Brandon Mistretta,
Sujina Mali, Preethi Gunaratne, Steven J. Bark, Jerry O. Ebalunode, Arshad Khan, William
R. Widger, Mehmet Sen. Functional and structural characterization of Hyp730, a highly
conserved and dormancy‐specific hypothetical membrane protein. Microbiologyopen. 2021 Jan; 10(1): e1154. Published online 2021 Feb 3. doi: 10.1002/mbo3.1154. PMCID:
PMC7856521
Andrew J. Davis, Maksym Tsinkevich, Jason Rodencal, Hussein A. Abbas, Xiao-hua Su,
Young-Jin Gi, Bin Fang, Kimal Rajapakshe, Cristian Coarfa, Preethi H. Gunaratne, John
M. Koomen, Kenneth Y. Tsai, Elsa R. Flores. TAp63-regulated microRNAs suppress cutaneous
squamous cell carcinoma through inhibition of a network of cell cycle genes. Cancer
Res. 2020 Jun 15; 80(12): 2484-2497. PMCID: PMC7299759
Raghunathan S, Islas JF, Mistretta B, Iyer D, Shi L, Gunaratne PH, Ko G, Schwartz
RJ, McConnell BK. Conversion of human cardiac progenitor cells into cardiac pacemaker-like
cells. J Mol Cell Cardiol. 2020 Jan;138:12-22. doi: 10.1016/j.yjmcc.2019.09.015. Epub 2019 Oct 31. PMID: 31678351
Havis S, Bodunrin A, Rangel J, Zimmerer R, Murphy J, Storey JD, Duong TD, Mistretta
B, Gunaratne P, Widger WR, Bark SJ. A Universal Stress Protein that Controls Bacterial
Stress Survival in Micrococcus luteus. J Bacteriol. 2019 Sep 23. pii: JB.00497-19.
doi: 10.1128/JB.00497-19. PMID: 31548273
Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y, Xia W, Gong J, Pan
Y, Chatterjee SS, Yao J, Evans KW, Nguyen TK, Park PK, Liu J, Coarfa C, Donepudi SR,
Putluri V, Putluri N, Sreekumar A, Ambati CR, Hawke DH, Marks JR, Gunaratne PH, Caudle
AS, Sahin AA, Hortobagyi GN, Meric-Bernstam F, Chen L, Yu D, Hung MC, Curran MA, Han
L, Lin C, Yang L. Oncogenic lncRNA downregulates cancer cell antigen presentation
and intrinsic tumor suppression. Nat Immunol. 2019 Jun 3. doi: 10.1038/s41590-019-0400-7. PMID:31160797
Maria Moreno-Villanueva, Ye Zhang, Alan Feiveson, Brandon Mistretta, Yinghong Pan,
Sujash Chatterjee, Winston Wu, Ryan Clanton, Mayra, Nelman-Gonzalez, Stephanie Krieger,
Preethi Gunarantne, Brian Crucian, Honglu Wu. Single-cell RNA-sequencing identifies
activation of TP53 and STAT1 pathways in human T lymphocyte subpopulations in response
to ex vivo radiation exposure. Int. J. Mol. Sci. 2019, ijms-487137
Chen C, Meng Q, Xia Y, Ding C, Wang L, Dai R, Cheng L, Gunaratne P, Gibbs RA, Min
S, Coarfa C, Reid JG, Zhang C, Jiao C, Jiang Y, Giase G, Thomas A, Fitzgerald D, Brunetti
T, Shieh A, Xia C, Wang Y, Wang Y, Badner JA, Gershon ES, White KP, Liu C. The transcription
factor POU3F2 regulates a gene coexpression network in brain tissue from patients
with psychiatric disorders. Sci Transl Med. 2018 Dec 13. pii: eaat8178. doi: 10.1126/scitranslmed.aat8178.
PMID:30545964